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  • 张潇月,蔡成*.支气管肺发育不良相关药物治疗研究进展[J].第二军医大学学报,2018,39(10):1149-1152    [点击复制]
  • ZHANG Xiao-yue,CAI Cheng*.Advances in drug therapy of bronchopulmonary dysplasia[J].Acad J Sec Mil Med Univ,2018,39(10):1149-1152   [点击复制]
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支气管肺发育不良相关药物治疗研究进展
张潇月,蔡成*
0
(上海交通大学附属儿童医院、上海市儿童医院新生儿科, 上海 200062
*通信作者)
摘要:
支气管肺发育不良(BPD)是早产儿最严重的并发症之一,严重影响早产儿的生存质量。随着新生儿重症监护技术的不断提高,治疗BPD的方法越来越多,但是效果仍不理想,争议也颇多。药物治疗作为一种常规的治疗方法,仍然在BPD的预防和治疗中占有非常重要的地位。本文总结分析临床常用的BPD防治药物的研究进展,为更有效地防治BPD提供参考。
关键词:  支气管肺发育不良  糖皮质激素类  维生素A  咖啡因
DOI:10.16781/j.0258-879x.2018.10.1149
投稿时间:2018-03-03修订日期:2018-05-04
基金项目:国家自然科学基金(81571467).
Advances in drug therapy of bronchopulmonary dysplasia
ZHANG Xiao-yue,CAI Cheng*
(Department of Neonatology, Shanghai Children's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200062, China
*Corresponding author)
Abstract:
Bronchopulmonary dysplasia (BPD) is one of the most serious complications of preterm infants and seriously affects the quality of life of premature infants. With the continuous improvement of neonatal intensive care technology, more and more methods were used for the treatment of BPD, but the effect is still not satisfactory and has controversies. As a routine treatment, drug therapy plays an important role in the prevention and treatment of BPD. In this paper, we summarized the research progress of commonly used clinical drugs for BPD, and proposed possible effective ways for the prevention and treatment of BPD.
Key words:  bronchopulmonary dysplasia  corticosteroids  vitamin A  caffeine