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  • 戚中田*.严重急性呼吸综合征冠状病毒2与新型冠状病毒肺炎[J].第二军医大学学报,2020,41(2):117-121    [点击复制]
  • QI Zhong-tian*.Severe acute respiratory syndrome coronavirus 2 and coronavirus disease 2019[J].Acad J Sec Mil Med Univ,2020,41(2):117-121   [点击复制]
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严重急性呼吸综合征冠状病毒2与新型冠状病毒肺炎
戚中田*
0
(海军军医大学(第二军医大学)海军医学系生物医学防护教研室, 全军生物侦检与防护重点实验室, 上海市医学生物防护重点实验室, 上海 200433
*通信作者)
摘要:
目前正在暴发流行的新型冠状病毒肺炎(COVID-19)的病原体是严重急性呼吸综合征冠状病毒2(SARS-CoV-2),这是近年来继严重急性呼吸综合征冠状病毒(SARS-CoV)和中东呼吸综合征冠状病毒(MERSCoV)之后发现的能够感染人的第7种冠状病毒。SARS-CoV-2系单股正链RNA病毒,传染性强,人群普遍对其缺乏免疫力,疫情目前仍在持续。2020年1月30日(当地时间),WHO将此次疫情列为国际关注的突发公共卫生事件(PHEIC)。本文就SARS-CoV-2病原学、致病性及COVID-19的检测诊断、预防控制和临床治疗等领域的进展进行讨论。
关键词:  严重急性呼吸综合征冠状病毒2  新型冠状病毒肺炎  病原学  诊断  预防  治疗
DOI:10.16781/j.0258-879x.2020.02.0117
投稿时间:2020-02-07修订日期:2020-02-13
基金项目:国家传染病重大专项课题(2017ZX10304403-003).
Severe acute respiratory syndrome coronavirus 2 and coronavirus disease 2019
QI Zhong-tian*
(Department of Biomedical Defense, PLA Key Laboratory of Biodetection and Biodefense, Shanghai Key Laboratory of Medical Biodefense, Faculty of Naval Medicine, Naval Medical University(Second Military Medical University), Shanghai 200433, China
*Corresponding author)
Abstract:
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been confirmed as the etiological pathogen of the coronavirus disease 2019 (COVID-19). SARS-CoV-2 is the seventh member of coronavirus family that can infect humans after the emergence of the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV). SARS-CoV-2 is a single-stranded, positive-sense RNA virus. Due to its strong infectiousness and the lack of immunity in humans, the epidemic of the COVID-19 is still spreading. On January 30, 2020 (local time), the World Health Organization (WHO) defined the epidemics of SARS-CoV-2-infected pneumonia as a Public Health Emergency of International Concern (PHEIC). This paper reviews the etiology and pathogenicity of SARS-CoV-2, and the detection and diagnosis, prevention and control, as well as the treatment of COVID-19.
Key words:  severe acute respiratory syndrome coronavirus 2  coronavirus disease 2019  etiology  diagnosis  prevention  treatment